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Review of Recent Studies on Anti-Diabetes Supplements

Some vitamins and supplements may help those with diabetes or prediabetes control their blood sugar levels. This article reviews the findings of recent studies on so-called “anti-diabetes” supplements like Ayurvedic capsules for diabetes.

Aloe Vera

For a long time, people have assumed that aloe vera may help reduce their blood sugar levels.

Glycemic (blood glucose) management was shown to be enhanced in those with prediabetes and type 2 diabetes who took oral aloe vera, according to a meta-analysis of eight clinical trials published in 2016. Researchers acknowledged the first results were weak due to poor study quality and called for more randomized controlled trials.


The ubiquitous mineral magnesium is crucial for maintaining healthy levels of blood pressure, muscular function, heart rhythm, and blood sugar.

Higher magnesium intake is associated with a reduced incidence of diabetes, suggesting that magnesium may have a function in glucose metabolism.

Oral magnesium supplementation was shown to enhance glycemic management and decrease insulin resistance in adults with type 2 diabetes, according to a research published in 2019.

Bitter Melon

The fruit known as bitter melon, or Momordica charantia, has been utilized for generations in traditional Indian medicine. Since it is thought to contain powerful anti-diabetic compounds, it is often used as a herbal therapy for diabetes.

A 2011 paper hypothesized that bitter melon capsules include at least one chemical for inhibitory action against the formation of a particular enzyme—11-HSD1. However, there are not many definitive studies examining the effect of bitter melon on decreasing blood sugar levels. It is believed that this causes hyperglycemia by converting cortisone into cortisol. The authors speculate that the anti-diabetic effects of this fruit may be due to its inhibitory effect.

Gymnema or Gurmar

Gymnema sylvestre, also known as Gymnema (Gurmar) in Hindi, is a woody perennial vine native to the tropics of India, China, Australia, and certain areas of Africa. In Ayurvedic medicine, it is often employed.

Sugar cravings may be reduced by using this herb, according to studies. It may also slow the pace at which sugar is absorbed by the body, making it useful in the management of diabetes.


Some dietary sources naturally contain the mineral chromium. Chromium may be found in two different oxidation states, hexavalent (6+) and trivalent (3+). The most common type, and the one found in food, is the trivalent form. Toxic in its hexavalent form, it is often found in industrial waste and pollution and should be avoided.

Alpha-Lipoic Acid

Alpha-lipoic acid is a chemical that may be found in the nucleus of every human cell. It uses oxygen to turn the glucose in your blood into usable energy. Aerobic metabolism describes this process.

Several research on alpha-lipoic acid’s efficacy were analyzed in a 2019 review. The results of the study are inconsistent. Some studies found alpha-lipoic acid to be helpful, while others found it to be no better than placebo. The authors concluded that more trials with bigger samples are necessary to draw firm conclusions on efficacy.


Certain foods contain beneficial bacteria known as probiotics, and these bacteria may help diabetics control their blood sugar levels. These “good” bacteria assist in the digestion of carbohydrates that may otherwise lead to hyperglycemia by sustaining the normal bacterial and fungal flora in the gut.

You may get these “good” bacteria into your system in a concentrated form through probiotic pills as well as probiotic meals.

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